Hair loss and hair thinning is a result of testosterone formed in different areas like the prostate gland or hair follicles, which is converted to Dihydrotestosterone (DHT) in the scalp area.  Hair follicles prone to genetic male patterned baldness contain DHT receptors, thus thinning hair and loss of hair can result.  Over time men produce an abundance of DHT and the molecules affect their hair follicles and cause a decrease in size and eventually see their natural hair fall out permanently. Because of this common occurrence, hair loss in men is frequent.

DHT and hair loss from having the gene for male pattern baldness are the most common factors for male pattern baldness. Women suffering from female-pattern baldness, unlike their counterparts with male-pattern baldness, are not usually characterized by higher production rates of DHT from lower levels of testosterone. On the other hand, if for a number of possible reasons, a woman has increased testosterone, she can develop female patterned baldness like a man does through the same mechanism.

Hair in the prone areas to male patterned baldness: Corners, top, and crown are filled with DHT receptors in men who suffer Androgenic Alopecia The hair on donor areas such as back and sides, however, have fewer DHT receptors.  This is precisely why hair is more permanent on the sides and back and not the top and front.

The distinction in the hair quality of different areas, such as the donor and recipient areas, allows for hair loss surgeons to remove the hair from one area and transplant it to the bald portions of the scalp.  These newly transplanted hairs are permanent and immune to DHT. Finasteride (Propecia) is a drug which blocks the conversion of testosterone to DHT as a result of it blocking the enzyme alpha reductase.  The amount of DHT in hair loss patients decrease when they are on Propecia and this helps to maintain healthy hair, and also helps some of the miniaturized hair become stronger.

We at US Hair Restoration often recommend medical treatment with DHT blockers in many of our patients who undergo a hair transplantation procedure in order to help maintain their own hair in addition to the newly restored, formerly balding areas because of a hair restoration surgery.

There was an article I came across about artificial hair transplantation. The practice of artificial hair or synthetic hair transplantation to treat hair loss or androgenetic alopecia has yet to be approved by the FDA. But, in other countries, artificial hair restoration is being attempted. In addition, in the Journal of Cosmetic Dermatology, there was a study published about artificial hair transplants, but the results are to be taken with a grain of salt as there weren’t a lot of participants. Nevertheless, it’s worth mentioning.

Mentioned in the article were issues in the artificial hair implant process, which included: ineffective techniques, poor quality of hair fiber, and inexperienced surgeons. But, it’s important to note, the study’s aim is to convey the idea that artificial copolyamide fiber implantation seems to be relatively safe and a possible remedy to male pattern baldness or androgenetic alopecia.

The study consisted of 10 androgenetic alopecia adult test subjects who had tried more mainstream hair restoration techniques but to no avail; these test subjects agreed to have copolyamide fiber implanted on their scalps and were followed a minimum of three years. Initial implants included 100 fibers followed by subsequent sessions of up to 500 fibers per four to six weeks for the purpose of achieving a density of 20-40 fibers per cm2.

Throughout the study, during fiber implants and follow-up sessions, the researchers maintained an almost exact adherence to schedule. For the study as a whole, 10,000 fibers were implanted; for each test subject, an average of 1000 fibers. Overall (except for one person), researchers found that the implants resulted in pleasant-looking hair, didn’t have any notable side effects, and the subjects emotionally satisfied. At the entry point of most fibers, sebum deposition and temporary pitting were consistent throughout. In 30 percent of test subjects, there was a case of recurrent mild folliculitis.

In this study, common complications such as facial swelling, cellulitis, and severe scarring were not detected. It is important to note, each year, 15 percent to 30 percent of transplanted fibers fell away, which led to required regular maintenance. To conclude the study, factors of significant importance were the method of fiber transplant technique and consistent follow-up, leading to positive results. In the near future, hair transplants might be done with artificial hair for patients who don’t have quality donor hair and also are suffering from excessive baldness. But, much more testing is required to see whether artificial hair transplant can be an option for future hair loss patients.